Moscow, June 17 – AIF-Moscow.
Employees of the Moscow State University Lomonosov found a way to deal with renal failure in newborn children, the press service of the university reports. The results of their work are published in the publication Antioxidants.
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Scientists investigated the effect of antioxidant on newborn rats with induced renal failure and proved the effectiveness of the mitochondria-targeted antioxidant SkQR1 in combating this diagnosis. The study may be the basis for the development of a new drug for multiple organ and renal failure in infants.
Scientists simulated sepsis in newborn rat pups by injecting lipopolysaccharide into the bacterial cell wall, which resulted in damage to the tubular kidney cells. Introduction of an antioxidant three hours before the induction of sepsis protected the kidneys from damage so much that it helped them maintain their function.
Mitochondria-targeted antioxidant SkQR1 was developed under the guidance of Academician Vladimir Skulachev. Previously, scientists have proven that this compound has antibiotic properties, slows the aging of plants and helps wound healing in diabetes.
The study involved employees of the Scientific Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov, First Moscow State Medical University named after I.M. Sechenov and the Research Institute of Human Morphology.